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Vancouver Whitecaps FC kick off their Concacaf Champions Cup Round of 16 on Wednesday with a Leg 1 matchup with LIGA MX giant CF Monterrey at BC Place.

Seattle Sounders FC resume their 2025 Concacaf Champions Cup campaign Wednesday evening, when they host LIGA MX side Cruz Azul in a Round of 16 Leg 1 fixture.

Defending MLS Cup champions LA Galaxy begin their 2025 Concacaf Champions Cup campaign with a Round of 16 first-leg test at Costa Rican side Herediano on Wednesday evening.

Inter Miami CF continue their 2025 Concacaf Champions Cup campaign Thursday night when hosting Jamaican side Cavalier FC in Leg 1 of a Round of 16 series.

FC Cincinnati resume their 2025 Concacaf Champions Cup campaign Tuesday evening when they host LIGA MX powerhouse Tigres UANL for Leg 1 of a Round of 16 series.

A familiar MLS matchup awaits in the 2025 Concacaf Champions Cup, as LAFC host the Columbus Crew on Tuesday night for Leg 1 of their Round of 16 series.

Bring on the Round of 16. Seven MLS clubs remain in the 2025 Concacaf Champions Cup, with eyes on the trophy that grants a spot in the 2029 FIFA Club World Cup and 2025 FIFA Intercontinental Cup. The LA Galaxy (MLS Cup 2024 winners) and Columbus Crew (Leagues Cup 2024

TRANSFER TRACKER STATUS: Signing D.C. United have acquired winger Fidel Barajas on loan from LIGA MX's Chivas Guadalajara, the club announced Wednesday.

Vancouver Whitecaps FC will look to rebound from a 2-1 setback in Leg 1 when they host Costa Rican powerhouse Saprissa in a crucial Leg 2 of their 2025 Concacaf Champions Cup Round One series on Thursday night.

Seattle Sounders FC carry a 3-1 aggregate lead over Guatemalan side Antigua into Wednesday's decisive Leg 2 of their Concacaf Champions Cup Round One series.

Real Salt Lake and Costa Rican side Herediano are deadlocked at 0-0 entering Leg 2 of their 2025 Concacaf Champions Cup Round One series, which will be decided Wednesday night at America First Field.

FC Cincinnati hold a 4-1 aggregate lead over Motagua ahead of hosting Leg 2 of their 2025 Concacaf Champions Cup Round One series on Wednesday night.

With more goals scored across Saturday and Sunday than in any previous opening weekend in league history (and more teams scoring four-plus goals than in any opening weekend in the modern era), it’s safe to say the 2025 MLS season kicked off with a bang.

There's nothing quite like an MLS is Back tifo.

The Colorado Rapids hold a 2-1 aggregate advantage before visiting LAFC on Tuesday night for Leg 2 of their 2025 Concacaf Champions Cup Round One series.

Inter Miami CF hold a 1-0 aggregate advantage over Sporting Kansas City before hosting Leg 2 of their 2025 Concacaf Champions Cup Round One series on Tuesday night.

Major League Soccer (MLS) adheres to The International Football Association Board's (IFAB) Laws of the Game. Click here to view the 2024-25 Laws of the Game

TRANSFER TRACKER STATUS: Extension CF Montréal have signed veteran midfielder Samuel Piette to a contract extension through 2027 with an option for 2028, the club announced Friday.

Who are the emerging homegrowns you need to know?

TRANSFER TRACKER STATUS: Signing LA Galaxy have acquired striker Matheus Nascimento on loan from Brazilian top-flight side Botafogo, the reigning MLS Cup presented by Audi champions announced Wednesday.

It’s go time for San Diego FC.

TRANSFER TRACKER STATUS: Signing Chicago Fire FC have signed homegrown defender Christopher Cupps, the club announced Tuesday.

TRANSFER TRACKER STATUS: Trade - HOU receive: Michael Halliday - ORL receive: MLS SuperDraft pick, sell-on % Houston Dynamo FC have acquired right back Michael Halliday from Orlando City SC, the clubs announced Tuesday.

Vancouver Whitecaps FC kick off their 2025 Concacaf Champions Cup campaign Thursday night with a Round One Leg 1 match at Costa Rican side Deportivo Saprissa.

FC Cincinnati begin their 2025 Concacaf Champions Cup campaign Wednesday evening at Honduran side FC Motagua with Leg 1 of a Round One series.