Santos Laguna have proven to be a difficult obstacle for MLS clubs over the years in the Concacaf Champions League.
It was the case again in the 2019 Champions League quarterfinals with the New York Red Bulls falling to Santos 6-2 on aggregate over two legs.
With their 4-2 win over RBNY in the 2nd leg at Estadio Corona, Santos Laguna have compiled a 8W-0L-1D record with the lone blemish coming on a draw earned by the Seattle Sounders in the 2012-'13 Champions League semis.
Santos have made that home field advantage count in a big way in the knockout rounds of the Champions League, ousting the MLS club in all six series between 2012 and 2019.
MLS clubs vs. Santos Laguna in Concacaf Champions League:
- Santos Laguna def. Seattle Sounders 7-3 on aggregate goals (2011-'12 QFs)
- Santos Laguna def. Toronto FC 7-3 on aggregate goals (2011-'12 SFs)
- Santos Laguna def. Houston Dynamo 3-1 on aggregate goals (2012-'13 QFs)
- Santos Laguna def. Seattle Sounders 2-1 on aggregate goals (2012-'13 SFs)
- Santos Laguna def. LA Galaxy 4-0 on aggregate goals (2015-'16 QFs)
- Santos Laguna def. NY Red Bulls 6-2 on aggregate goals (2019 QFs)