The Lille winger’s slashing run was picked out by Chelsea winger Christian Pulisic with the Dragons' backline scrambling, then his outside-the-foot shot beat onrushing goalkeeper Wayne Hennessey for a 1-0 lead.
Weah’s goal came after the USMNT dominated early proceedings, then provided their reward shortly before halftime. The 22-year-old New York native, who plays in Ligue 1, is the son of former Ballon d'Or winner and Liberia president George Weah.
Carrying a deserved advantage, manager Gregg Berhalter's side are looking to begin their Qatar 2022 campaign on the winning foot and keep pace with England, who trounced Iran, 6-2, in Monday's first match.
The USMNT, who have the second-youngest roster in the tournament, are in their first World Cup since Brazil 2014. They also play England (Nov. 25) and Iran (Nov. 29) in Group B, with the top two finishers advancing to the Round of 16.