The 31-year-old Spanish maestro was just coming off an injury when the two teams met in the CONCACAF Champions League quarterfinals back in March and he only saw a handful of minutes across both legs as Toronto knocked out Tigres in an epic encounter.
Vazquez is now back to full health, starting six of Toronto FC's last eight league matches and he's looking forward to the match at BMO Field (8 pm ET on Univision; 8:30 pm ET on ESPN2, TSN and TVA Sports).
"I'm really happy to play against the best team in Mexico and try to beat them," he told MLSsoccer.com in reference to Tigres. "For sure it's going to be fun because they [Tigres] love to play soccer, like us ... I think the supporters are going to enjoy it a lot."
Campeones Cup pits the reigning MLS champion against the Liga MX champion in a one-off match with a trophy and bragging rights on the line.